Inhibitors of BRD4 Protein from a Marine-Derived Fungus Alternaria sp. NH-F6

Bromodomains (BRD) are readers of the epigenetic code that regulate gene transcription through their recognition of acetyl-lysine modified histone tails. Recently, bromodomain-containing proteins such as BRD4 have been demonstrated to be druggable through the discovery of potent inhibitors. These pr...

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Bibliographic Details
Main Authors: Hui Ding, Dashan Zhang, Biao Zhou, Zhongjun Ma
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/15/3/76