Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation

Summary: Dermal γδT cells play critical roles in skin homeostasis and inflammation. However, the underlying molecular mechanisms by which these cells are activated have not been fully understood. Here, we show that the mechanistic or mammalian target of rapamycin (mTOR) and STAT3 pathways are activa...

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Bibliographic Details
Main Authors: Yihua Cai, Feng Xue, Hui Qin, Xu Chen, Na Liu, Chris Fleming, Xiaoling Hu, Huang-ge Zhang, Fuxiang Chen, Jie Zheng, Jun Yan
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719306308