NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients

NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients

Mitochondrial DNA (mtDNA) mutations are closely implicated in the pathogenesis of multiple cancers, making circulating cell-free mtDNA (ccf-mtDNA) as a potential non-invasive tumor biomarker. However, an effective approach to comprehensively profile ccf-mtDNA mutations is still lacking. In this stud...

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Bibliographic Details
Main Authors: Yang Liu, Kaixiang Zhou, Shanshan Guo, Yang Wang, Xiaoying Ji, Qing Yuan, Liping Su, Xu Guo, Xiwen Gu, Jinliang Xing
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312030398X

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http://www.sciencedirect.com/science/article/pii/S216225312030398X

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