Small Extracellular Vesicles Released from Ovarian Cancer Spheroids in Response to Cisplatin Promote the Pro-Tumorigenic Activity of Mesenchymal Stem Cells

Small Extracellular Vesicles Released from Ovarian Cancer Spheroids in Response to Cisplatin Promote the Pro-Tumorigenic Activity of Mesenchymal Stem Cells

Despite the different strategies used to treat ovarian cancer, around 70% of women/patients eventually fail to respond to the therapy. Cancer stem cells (CSCs) play a role in the treatment failure due to their chemoresistant properties. This capacity to resist chemotherapy allows CSCs to interact wi...

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Bibliographic Details
Main Authors: Nelly Vera, Stephanie Acuña-Gallardo, Felipe Grünenwald, Albano Caceres-Verschae, Ornella Realini, Rodrigo Acuña, Alvaro Lladser, Sebastián E. Illanes, Manuel Varas-Godoy
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
small extracellular vesicles
cancer stem cells
spheroids
cisplatin
tumor microenvironment
bone marrow mesenchymal stem cells
Online Access:https://www.mdpi.com/1422-0067/20/20/4972

Internet

https://www.mdpi.com/1422-0067/20/20/4972

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