A Cytokine Network Balance Influences the Fate of Leishmania (Viannia) braziliensis Infection in a Cutaneous Leishmaniasis Hamster Model

A Cytokine Network Balance Influences the Fate of Leishmania (Viannia) braziliensis Infection in a Cutaneous Leishmaniasis Hamster Model

The golden hamster is a suitable model for studying cutaneous leishmaniasis (CL) due to Leishmania (Viannia) braziliensis. Immunopathological mechanisms are well established in the L. (L.) major-mouse model, in which IL-4 instructs a Th2 response towards progressive infection. In the present study,...

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Bibliographic Details
Main Authors: Milla B. Paiva, Raquel Peralva Ribeiro-Romão, Larissa Resende-Vieira, Thais Braga-Gomes, Marcia P. Oliveira, Andrea F. Saavedra, Luzinei Silva-Couto, Hermano G. Albuquerque, Otacilio C. Moreira, Eduardo Fonseca Pinto, Alda Maria Da-Cruz, Adriano Gomes-Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
cytokines
cutaneous lesions
parasite load
disease control
Leishmania (Viannia) braziliensis
iNOS/arginase
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.656919/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.656919/full

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