Comparative <i>In Vitro</i> Study of Various α<sub>2</sub>-Adrenoreceptor Agonist Drugs for Ticagrelor Reversal

Comparative <i>In Vitro</i> Study of Various α<sub>2</sub>-Adrenoreceptor Agonist Drugs for Ticagrelor Reversal

Ticagrelor, an antiplatelet adenosine diphosphate (ADP)-P2Y<sub>12</sub> receptor antagonist, increases the risk of bleeding. Its management is challenging because platelet transfusion is ineffective and no specific antidote is currently available. Epinephrine, a vasopressor catecholamin...

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Bibliographic Details
Main Authors: Guillaume Porta Bonete, Anne Godier, Pascale Gaussem, Tiphaine Belleville-Rolland, Alexandre Leuci, Sonia Poirault-Chassac, Christilla Bachelot-Loza, Anne-Céline Martin
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Journal of Clinical Medicine
Subjects:
antiplatelet agent
ticagrelor
reversal
α<sub>2</sub>-agonist
Online Access:https://www.mdpi.com/2077-0383/9/3/809

Internet

https://www.mdpi.com/2077-0383/9/3/809

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