Characterization of Chicken IgY Specific to Clostridium difficile R20291 Spores and the Effect of Oral Administration in Mouse Models of Initiation and Recurrent Disease

Characterization of Chicken IgY Specific to Clostridium difficile R20291 Spores and the Effect of Oral Administration in Mouse Models of Initiation and Recurrent Disease

Clostridium difficile infection (CDI) are the leading cause of world-wide nosocomial acquired diarrhea. The current main clinical challenge in CDI is the elevated rate of infection recurrence that may reach up to 30% of the patients, which has been associated to the formation of dormant spores durin...

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Bibliographic Details
Main Authors: Marjorie Pizarro-Guajardo, Fernando Díaz-González, Manuel Álvarez-Lobos, Daniel Paredes-Sabja
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Clostridium difficile spores
chicken immunoglobulin IgY
immunotherapy
passive immunization
recurrent CDI
exosporium
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00365/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2017.00365/full

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