Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord.

Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord.

Neuromyelitis optica (NMO) is an acute inflammatory disease of the central nervous system (CNS) which predominantly affects spinal cord and optic nerves. Most patients harbor pathogenic autoantibodies, the so-called NMO-IgGs, which are directed against the water channel aquaporin 4 (AQP4) on astrocy...

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Bibliographic Details
Main Authors: Satoru Oji, Eva-Maria Nicolussi, Nathalie Kaufmann, Bleranda Zeka, Kathrin Schanda, Kazuo Fujihara, Zsolt Illes, Charlotte Dahle, Markus Reindl, Hans Lassmann, Monika Bradl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0151244

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https://doi.org/10.1371/journal.pone.0151244

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