Synthesis, Biological Evaluation and Molecular Docking Studies of Ferrocene Derivatives Coupling with N-heterocyclic on Human Breast Cancer
A series of heterocyclic ferrocene derivatives (Fc1–Fc18) was designed and synthesized. The eight representative target compounds were evaluated for their antitumor activities against human breast cancer (MCF-7) cells using MTT assay. Compounds Fc3, Fc11, Fc12, and Fc17 inhibited MCF-7 cells at IC50...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2015-01-01
|
| Series: | MATEC Web of Conferences |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1051/matecconf/20152205001 |