ERK/MAPK is essential for endogenous neuroprotection in SCN2.2 cells.

Glutamate (Glu) is essential to central nervous system function; however excessive Glu release leads to neurodegenerative disease. Strategies to protect neurons are underdeveloped, in part due to a limited understanding of natural neuroprotective mechanisms, such as those present in the suprachiasma...

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Bibliographic Details
Main Authors: Sumedha W Karmarkar, Kathleen M Bottum, Stacey L Krager, Shelley A Tischkau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3157406?pdf=render