Genome-wide and cell-specific epigenetic analysis challenges the role of polycomb in Drosophila spermatogenesis.

The Drosophila spermatogenesis cell differentiation pathway involves the activation of a large set of genes in primary spermatocytes. Most of these genes are activated by testis-specific TATA-binding protein associated factors (tTAFs). In the current model for the activation mechanism, Polycomb play...

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Bibliographic Details
Main Authors: Sherif El-Sharnouby, Juliet Redhouse, Robert A H White
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3798269?pdf=render