Locus Coeruleus tracking of prediction errors optimises cognitive flexibility: An Active Inference model.

The locus coeruleus (LC) in the pons is the major source of noradrenaline (NA) in the brain. Two modes of LC firing have been associated with distinct cognitive states: changes in tonic rates of firing are correlated with global levels of arousal and behavioural flexibility, whilst phasic LC respons...

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Bibliographic Details
Main Authors: Anna C Sales, Karl J Friston, Matthew W Jones, Anthony E Pickering, Rosalyn J Moran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006267