Simvastatin assay and dissolution studies by feasible RP-HPLC in tablets
Commonly used HPLC acetonitrile solvent has been through a worldwide shortage with a cost increase in 2008 and 2009. In order to get around this situation, a method by RP-HPLC employing methanol and aqueous acid mobile phase was developed and validated to evaluate simvastatin. The quality control as...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Química
2012-01-01
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Series: | Química Nova |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600031&lng=en&tlng=en |