ALPHA–2–MACROGLOBULIN COMPLEXES WITH IGG ANTIBODIES, PLASMIN, AND THEIR INTERRELATION WITH OTHER FACTORS OF HUMORAL IMMUNITY DURING THE DEVELOPMENT OF RHEUMATOID ARTHRITIS

ALPHA–2–MACROGLOBULIN COMPLEXES WITH IGG ANTIBODIES, PLASMIN, AND THEIR INTERRELATION WITH OTHER FACTORS OF HUMORAL IMMUNITY DURING THE DEVELOPMENT OF RHEUMATOID ARTHRITIS

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<p><strong>Abstract. </strong>Human alpha–2–macroglobulin (α2–MG) acts as a broad–spectrum cytokine and proteasebinding protein, and it represents an evolutionarily conserved arm of innate immune system. Meanwhile, previous studies have shown that rheumatoid arthritis (RA) developm...

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Bibliographic Details
Main Authors: V. N. Zorina, N. A. Trofimenko, S. V. Arkhipova, R. M. Zorina, N. A. Zorin
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
alpha-2-macroglobulin
rheumatoid arthritis
autoantibodies
cytokines
Online Access:http://mimmun.ru/index.php/mimmun/article/view/623

Internet

http://mimmun.ru/index.php/mimmun/article/view/623

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