Interspecies translation of disease networks increases robustness and predictive accuracy.

Gene regulatory networks give important insights into the mechanisms underlying physiology and pathophysiology. The derivation of gene regulatory networks from high-throughput expression data via machine learning strategies is problematic as the reliability of these models is often compromised by li...

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Bibliographic Details
Main Authors: Seyed Yahya Anvar, Allan Tucker, Veronica Vinciotti, Andrea Venema, Gert-Jan B van Ommen, Silvere M van der Maarel, Vered Raz, Peter A C 't Hoen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3207951?pdf=render