Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus

Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus

Lichen planus (LP) is a common, chronic relapsing inflammatory disorder of the skin and mucous membranes which often poses a major therapeutic challenge due to its refractory course. Novel pathogenesis-based therapies are urgently needed. As several studies have shown that IL-17 may contribute to LP...

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Bibliographic Details
Main Authors: Farzan Solimani, Robert Pollmann, Thomas Schmidt, Ansgar Schmidt, Xiang Zheng, Rajkumar Savai, Stefan Mühlenbein, Julia Pickert, Verena Eubel, Christian Möbs, Rüdiger Eming, Michael Hertl
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
lichen planus
IL-17
secukinumab
ustekinumab
guselkumab
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01808/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01808/full

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