Delayed NK Cell Reconstitution and Reduced NK Activity Increased the Risks of CMV Disease in Allogeneic-Hematopoietic Stem Cell Transplantation

Delayed NK Cell Reconstitution and Reduced NK Activity Increased the Risks of CMV Disease in Allogeneic-Hematopoietic Stem Cell Transplantation

Cytomegalovirus (CMV) infection has a significant impact in patients after allogeneic hematopoietic stem cell transplantation (HSCT). We investigated natural killer (NK) cell reconstitution and cytotoxic/cytokine production in controlling CMV infection, especially severe CMV disease in HSCT patients...

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Bibliographic Details
Main Authors: Ki Hyun Park, Ji Hyeong Ryu, Hyunjoo Bae, Sojeong Yun, Joo Hee Jang, Kyungja Han, Byung Sik Cho, Hee-Je Kim, Hyeyoung Lee, Eun-Jee Oh
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
cytomegalovirus
hematopoietic stem cell transplantation
acute myeloid leukemia
NK cells
NK cell-mediated antibody-dependent cellular cytotoxicity
NK subsets
Online Access:https://www.mdpi.com/1422-0067/21/10/3663

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https://www.mdpi.com/1422-0067/21/10/3663

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