MiR-15b Targets Cyclin D1 to Regulate Proliferation and Apoptosis in Glioma Cells

Aim. To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. Methods. The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Met...

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Bibliographic Details
Main Authors: Guan Sun, Lei Shi, Shushan Yan, Zhengqiang Wan, Nan Jiang, Linshan Fu, Min Li, Jun Guo
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/687826