Cooling produces minimal neuropathology in neocortex and hippocampus

Cooling is a potential treatment for several neurological diseases. We have examined rodent and cat neocortex, cooled to 5 and 3°C, respectively, to identify a lower limit for safely cooling brain. Rat neocortex, intermittently cooled with a thermoelectric device for 2 h, showed no signs of neuronal...

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Bibliographic Details
Main Authors: Xiao-Feng Yang, Bryan R. Kennedy, Stephen G. Lomber, Robert E. Schmidt, Steven M. Rothman
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106001227