A rapid method to assess the hydrophobicity of the intestinal microvillus membrane in vivo.

Absorption rates for many biologically important compounds are determined by the relative hydrophobicity of the jejunal microvillus membrane. An estimate of this parameter may be obtained by measuring the incremental change in free energy that occurs when a methylene group partitions into the bilaye...

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Bibliographic Details
Main Authors: J B Meddings, J M Dietschy
Format: Article
Language:English
Published: Elsevier 1989-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520382857