Assessment of effectiveness and safety of repeat administration of proinflammatory primed allogeneic mesenchymal stem cells in an equine model of chemically induced osteoarthritis

Assessment of effectiveness and safety of repeat administration of proinflammatory primed allogeneic mesenchymal stem cells in an equine model of chemically induced osteoarthritis

Abstract Background This study aimed at assessing the effectiveness and safety of repeated administrations of allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) primed with tumor necrosis factor (TNF)-α and interferon-γ in an equine model of chemically-induced osteoarthritis. Arthritis...

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Bibliographic Details
Main Authors: Laura Barrachina, Ana Rosa Remacha, Antonio Romero, Arantza Vitoria, Jorge Albareda, Marta Prades, Mercedes Roca, Pilar Zaragoza, Francisco José Vázquez, Clementina Rodellar
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Veterinary Research
Subjects:
Cartilage
Horse
Joint pathology
Immunogenicity
Immunomodulation
Synovial fluid
Online Access:http://link.springer.com/article/10.1186/s12917-018-1556-3

Internet

http://link.springer.com/article/10.1186/s12917-018-1556-3

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