Reduced skin lipid content in obese Japanese women mediated by decreased expression of rate-limiting lipogenic enzymes.

Skin barrier function is often deficient in obese individuals, but the underlying molecular mechanisms remain unclear. This study investigated how skin structure and lipid metabolism, factors strongly associated with barrier function, differed among 50 Japanese women of greatly varying body mass ind...

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Bibliographic Details
Main Authors: Yoshiko Horie, Hiroko Makihara, Kazumasa Horikawa, Fumika Takeshige, Ai Ibuki, Toshihiko Satake, Kazunori Yasumura, Jiro Maegawa, Hideaki Mitsui, Kenichi Ohashi, Tomoko Akase
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5843255?pdf=render