Long-Term Durability of Tenofovir-Based Antiretroviral Therapy in Relation to the Co-Administration of Other Drug Classes in Routine Clinical Practice.

In clinical trials, toxicity leading to tenofovir disoproxil fumarate (TDF) discontinuation is rare (3% by 2 years); however in clinical practice it seems to be higher, particularly when TDF is co-administered with ritonavir-boosted protease inhibitors (PI/r). Aims of this study were to assess the r...

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Main Authors: Silvia Costarelli, Alessandro Cozzi-Lepri, Giuseppe Lapadula, Stefano Bonora, Giordano Madeddu, Franco Maggiolo, Andrea Antinori, Massimo Galli, Giovanni Di Perri, Pierluigi Viale, Antonella d'Arminio Monforte, Andrea Gori, ICONA Foundation Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5055315?pdf=render