Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs

Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs

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Potent induction of fetal hemoglobin (HbF) production results in alleviating the complications of β-thalassemia and sickle cell disease (SCD). HbF inducer agents can trigger several molecular signaling pathways critical for erythropoiesis. Janus kinase/Signal transducer and activator of transcriptio...

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Bibliographic Details
Main Authors: Fakher Rahim, Hossein Allahmoradi, Fatemeh Salari, Mohammad Shahjahani, Ali Dehghani Fard, Seyed Ahmad Hosseini, Hadi Mousakhani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2013-07-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
β-thalassemia
Sickle Cell Disease
Fetal Hemoglobin
Online Access:http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/396/429

Internet

http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/396/429

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