Alterations in Sensitivity to Estrogen, Dihydrotestosterone, and Xenogens in B-Lymphocytes from Children with Autism Spectrum Disorder and Their Unaffected Twins/Siblings

It has been postulated that androgen overexposure in a susceptible person leads to excessive brain masculinization and the autism spectrum disorder (ASD) phenotype. In this study, the responses to estradiol (E2), dihydrotestosterone (DHT), and dichlorodiphenyldichloroethylene (DDE) on B-lymphocytes...

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Bibliographic Details
Main Authors: Martyn A. Sharpe, Taylor L. Gist, David S. Baskin
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2013/159810