Thermosensitive hydrogel designed for improving the antidepressant activities of genipin via intranasal delivery

The release of drugs in the brain is a challenge due to the blood–brain barrier, but intranasal administration of hydrogels enables the continuous release and quick targeting of drugs into the brain. The aim of this study was to prepare a genipin/hydroxypropyl-β-cyclodextrin inclusion complex thermo...

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Bibliographic Details
Main Authors: Xue-Jie Qi, Dong Xu, Meng-Li Tian, Jin-Feng Zhou, Qiang-Song Wang, Yuan-Lu Cui
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521003695