MmpS5-MmpL5 Transporters Provide <i>Mycobacterium smegmatis </i>Resistance to imidazo[1,2-<i>b</i>][1,2,4,5]tetrazines

MmpS5-MmpL5 Transporters Provide <i>Mycobacterium smegmatis </i>Resistance to imidazo[1,2-<i>b</i>][1,2,4,5]tetrazines

The emergence and spread of drug-resistant <i>Mycobacterium tuberculosis </i>strains (including MDR, XDR, and TDR) force scientists worldwide to search for new anti-tuberculosis drugs. We have previously reported a number of imidazo[1,2-<i>b</i>][1,2,4,5]tetrazines &#8722...

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Bibliographic Details
Main Authors: Dmitry A. Maslov, Kirill V. Shur, Aleksey A. Vatlin, Valery N. Danilenko
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pathogens
Subjects:
mycobacterium smegmatis
imidazo[1,2-b][1,2,4,5]tetrazine
mmps5-mmpl5
efflux
drug discovery
drug resistance
tuberculosis
Online Access:https://www.mdpi.com/2076-0817/9/3/166

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https://www.mdpi.com/2076-0817/9/3/166

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