NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment

NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment

Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease resulting from the inflammatory infiltration of exocrine glands, mainly salivary and lacrimal glands, leading to secretory dysfunction and serious complications including debilitating fatigue, systemic autoimmunity, and lymphoma. Like...

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Bibliographic Details
Main Authors: Elena Pontarini, Elisabetta Sciacca, Sofia Grigoriadou, Felice Rivellese, Davide Lucchesi, Liliane Fossati-Jimack, Rachel Coleby, Farzana Chowdhury, Francesca Calcaterra, Anwar Tappuni, Myles J. Lewis, Martina Fabris, Luca Quartuccio, Silvia Della Bella, Simon Bowman, Costantino Pitzalis, Domenico Mavilio, Salvatore De Vita, Michele Bombardieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Sjögren’s syndrome
salivary gland
NK cell
NKp30
epithelial cell
B7/H6
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.706737/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.706737/full

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