Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation

Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation

Chlorogenic acid (CGA) is a widely applied traditional Chinese medicine ingredient which can be used for the treatment of osteoporosis. In this experiment, we investigated the potential therapeutic effect of chlorogenic acid on thiram-induced tibial dyschondroplasia (TD) and explored the underlying...

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Bibliographic Details
Main Authors: Jialu Zhang, Shucheng Huang, Xiaole Tong, Lihong Zhang, Xiong Jiang, Hui Zhang, Khalid Mehmood, Jiakui Li
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
chlorogenic acid
growth plate
tibial dyschondroplasia
matrix mineralization
apoptosis
autophagy
Online Access:https://www.mdpi.com/1422-0067/20/13/3160

Internet

https://www.mdpi.com/1422-0067/20/13/3160

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