Downregulation of POFUT1 Impairs Secondary Myogenic Fusion Through a Reduced NFATc2/IL-4 Signaling Pathway
Past work has shown that the protein <i>O</i>-fucosyltransferase 1 (POFUT1) is involved in mammal myogenic differentiation program. <i>Pofut1</i> knockdown (Po −) in murine C2C12 cells leads to numerous elongated and thin myotubes, suggesting significant defects in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/18/4396 |