Adipose Tissue Hypoxia Correlates with Adipokine Hypomethylation and Vascular Dysfunction

Adipose Tissue Hypoxia Correlates with Adipokine Hypomethylation and Vascular Dysfunction

Obesity is characterized by the accumulation of dysfunctional adipose tissues, which predisposes to cardiometabolic diseases. Our previous in vitro studies demonstrated a role of hypoxia in inducing adipokine hypomethylation in adipocytes. We sought to examine this mechanism in visceral adipose tiss...

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Bibliographic Details
Main Authors: Mohamed M. Ali, Chandra Hassan, Mario Masrur, Francesco M. Bianco, Dina Naquiallah, Imaduddin Mirza, Patrice Frederick, Eduardo T. Fernandes, Cristoforo P. Giulianotti, Antonio Gangemi, Shane A. Phillips, Abeer M. Mahmoud
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
visceral adipose tissue
obesity
hypoxia
DNA methylation
TET1
inflammation
Online Access:https://www.mdpi.com/2227-9059/9/8/1034

Internet

https://www.mdpi.com/2227-9059/9/8/1034

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