DNA adenine methylation modulates pathogenicity of Klebsiella pneumoniae genotype K1

DNA adenine methylation modulates pathogenicity of Klebsiella pneumoniae genotype K1

Background/Purpose: Klebsiella pneumoniae genotype K1 is a highly virulent pathogen that causes liver abscess and metastatic endophthalmitis/meningitis. Whether its pathogenicity is controlled by DNA adenine methylase (Dam), an epigenetic regulator of bacterial virulence gene expression, is yet unkn...

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Bibliographic Details
Main Authors: Chi-Tai Fang, Wen-Ching Yi, Chia-Tung Shun, Shih-Feng Tsai
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
bacterial pathogenesis
DNA adenine methylation
genotype K1
Klebsiella pneumoniae
virulence regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118215008452

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http://www.sciencedirect.com/science/article/pii/S1684118215008452

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