The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

Sas-6 and Ana2/STIL proteins are required for centriole duplication and the homo-oligomerisation properties of Sas-6 help establish the ninefold symmetry of the central cartwheel that initiates centriole assembly. Ana2/STIL proteins are poorly conserved, but they all contain a predicted Central Coil...

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Bibliographic Details
Main Authors: Matthew A Cottee, Nadine Muschalik, Steven Johnson, Joanna Leveson, Jordan W Raff, Susan M Lea
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
centriole
centrosome
ultra-high resolution structure
SAS-6
Ana2
STIL
Online Access:https://elifesciences.org/articles/07236

Internet

https://elifesciences.org/articles/07236

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