Downregulation of notch signaling pathway in late preterm and term placentas from pregnancies complicated by preeclampsia.

Downregulation of notch signaling pathway in late preterm and term placentas from pregnancies complicated by preeclampsia.

Preeclampsia (PE) is a major cause of maternal mortality and morbidity, affecting 3-5% of all pregnancies. The Notch signaling pathway plays an important role during placental development, activating several target genes. Defects in the Notch pathway have adverse effect on placentation. The aim of t...

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Bibliographic Details
Main Authors: Persefoni Fragkiadaki, Nikolaos Soulitzis, Stavros Sifakis, Demetrios Koutroulakis, Victor Gourvas, Nikolaos Vrachnis, Demetrios A Spandidos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126163

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https://doi.org/10.1371/journal.pone.0126163

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