Interleukin-37 Ameliorates Influenza Pneumonia by Attenuating Macrophage Cytokine Production in a MAPK-Dependent Manner

Interleukin-37 Ameliorates Influenza Pneumonia by Attenuating Macrophage Cytokine Production in a MAPK-Dependent Manner

Viral pneumonitis caused by influenza A (H1N1) virus leads to high levels of morbidity and mortality. Given the limited treatment options for severe influenza pneumonia, it is necessary to explore effective amelioration approaches. Interleukin-37 (IL-37) has been reported to inhibit excessive immune...

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Bibliographic Details
Main Authors: Feifei Qi, Mingya Liu, Fengdi Li, Qi Lv, Guanpeng Wang, Shuran Gong, Shunyi Wang, Yanfeng Xu, Linlin Bao, Chuan Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
A/California/07/2009 (H1N1)
Interleukin-37
viral pneumonia
macrophages
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02482/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02482/full

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