Electrochemical Detection of Sequence-Specific DNA with the Amplification of Gold Nanoparticles

A sensitive electrochemical DNA biosensor was prepared based on mercaptoacetic acid (MAA)/gold nanoparticles (AuNPs) modified electrode. Probe DNA (NH2-DNA) was covalently linked to the carboxyl group of MAA in the presence of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and N-...

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Bibliographic Details
Main Authors: Yuzhong Zhang, Zhen Wang, Yuehong Wang, Lei Huang, Wei Jiang, Mingzhu Wang
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Electrochemistry
Online Access:http://dx.doi.org/10.4061/2011/619782