Attenuated Phenotype and Immunogenic Characteristics of a Mutated Herpes Simplex Virus 1 Strain in the Rhesus Macaque

Attenuated Phenotype and Immunogenic Characteristics of a Mutated Herpes Simplex Virus 1 Strain in the Rhesus Macaque

Herpes simplex virus type 1(HSV-1) presents a conundrum to public health worldwide because of its specific pathogenicity and clinical features. Some experimental vaccines, such as the recombinant viral glycoproteins, exhibit the viral immunogenicity of a host-specific immune response, but none of th...

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Bibliographic Details
Main Authors: Shengtao Fan, Xingli Xu, Yun Liao, Yongrong Wang, Jianbin Wang, Min Feng, Lichun Wang, Ying Zhang, Zhanlong He, Fengmei Yang, Nigel W. Fraser, Qihan Li
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Viruses
Subjects:
HSV-1
mutant strain
immunogenicity
rhesus macaques
Online Access:http://www.mdpi.com/1999-4915/10/5/234

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http://www.mdpi.com/1999-4915/10/5/234

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