Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract.

Radix Polygalae (the root of Polygala tenuifolia) is a herb widely used in traditional Asian medicine that is thought to exert a variety of neuropsychiatric effects. Radix Polygalae extract can protect against N-methyl D-aspartate (NMDA) neurotoxicity and induce brain-derived neurotrophic factor (BD...

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Main Authors: Im-Joon Shin, Sung Un Son, Hyunwoo Park, Yoorim Kim, Sung Hyun Park, Kelley Swanberg, Joo-Yeon Shin, Sang-Kyu Ha, Yoonju Cho, Soo-Yong Bang, Jae-Hwan Lew, Seung-Hun Cho, Sungho Maeng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3919798?pdf=render