Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition

Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition

Abstract Background Optogenetic silencing techniques have expanded the causal understanding of the functions of diverse neuronal cell types in both the healthy and diseased brain. A widely used inhibitory optogenetic actuator is eNpHR3.0, an improved version of the light-driven chloride pump halorho...

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Bibliographic Details
Main Authors: Chuanqiang Zhang, Shang Yang, Tom Flossmann, Shiqiang Gao, Otto W. Witte, Georg Nagel, Knut Holthoff, Knut Kirmse
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Biology
Subjects:
Halorhodopsin
eNpHR3.0
Optogenetic
Inhibition
Transgenic
Online Access:http://link.springer.com/article/10.1186/s12915-019-0717-6

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http://link.springer.com/article/10.1186/s12915-019-0717-6

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