CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy

CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy

Activation of multiple pathways is associated with cardiac hypertrophy and heart failure. We previously published that CXCR4 negatively regulates &#946;-adrenergic receptor (&#946;-AR) signaling and ultimately limits &#946;-adrenergic diastolic (Ca<sup>2+</sup>) accumulation...

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Bibliographic Details
Main Authors: Thomas J. LaRocca, Perry Altman, Andrew A. Jarrah, Ron Gordon, Edward Wang, Lahouaria Hadri, Mark W. Burke, Georges E. Haddad, Roger J. Hajjar, Sima T. Tarzami
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
chemokine receptor-4 (CXCR4)
CXCL12
cardiomyopathy
mitochondria
Online Access:https://www.mdpi.com/1422-0067/20/9/2267

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https://www.mdpi.com/1422-0067/20/9/2267

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