T-piece versus pressure-support ventilation for spontaneous breathing trials before extubation in patients at high risk of reintubation: protocol for a multicentre, randomised controlled trial (TIP-EX)

Introduction In intensive care unit (ICU), the decision of extubation is a critical time because mortality is particularly high in case of reintubation. To reduce that risk, guidelines recommend to systematically perform a spontaneous breathing trial (SBT) before extubation in order to mimic the pos...

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Main Authors: Christophe Guitton, Rémi Coudroy, Jean-Pierre Frat, Gwenaël Prat, Damien Contou, Jeremy Bourenne, Arnaud Gacouin, Jean Dellamonica, Guylaine Labro, Emmanuel Vivier, Stéphanie Ragot, Laurence Dangers, Guillaume Lacave, Béatrice Lacombe, Gael Pradel, Gaetan Beduneau, Anahita Rouze, Nicholas Sedillot, Alexandre Lautrette, Quentin Levrat, Marie-Ange Azais, Martin Dres, René Robert
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/11/e042619.full