Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer

Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer

Abstract Background Bladder cancer (BC) is one of the most common malignancies of the urinary tract. The role of transient receptor potential melastatin 7 (TRPM7) in BC remains unclear. The aim of this study was to investigate the function and signal transduction pathway of TRPM7 in BC. Methods T24...

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Bibliographic Details
Main Authors: Eun Hye Lee, So Young Chun, Bomi Kim, Bo Hyun Yoon, Jun Nyung Lee, Bum Soo Kim, Eun Sang Yoo, Sangkyu Lee, Phil Hyun Song, Tae Gyun Kwon, Yun-Sok Ha
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Urology
Subjects:
Bladder cancer
TRPM7
Src
Akt
JNK
Online Access:http://link.springer.com/article/10.1186/s12894-020-00714-2

Internet

http://link.springer.com/article/10.1186/s12894-020-00714-2

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