An enriched environment promotes synaptic plasticity and cognitive recovery after permanent middle cerebral artery occlusion in mice

An enriched environment promotes synaptic plasticity and cognitive recovery after permanent middle cerebral artery occlusion in mice

Cerebral ischemia activates an endogenous repair program that induces plastic changes in neurons. In this study, we investigated the effects of environmental enrichment on spatial learning and memory as well as on synaptic remodeling in a mouse model of chronic cerebral ischemia, produced by subject...

Full description

Bibliographic Details
Main Authors: Chuan-Jie Wang, Yi Wu, Qun Zhang, Ke-Wei Yu, Yu-Yang Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; environmental enrichment; cerebral ischemia; cognitive recovery; brain plasticity and reorganization; synaptic plasticity; electron microscopy; growth-associated protein 43; synaptophysin; postsynaptic density protein 95; permanent middle cerebral artery occlusion; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=3;spage=462;epage=469;aulast=Wang

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=3;spage=462;epage=469;aulast=Wang

Similar Items