The Multifaceted Antibacterial Mechanisms of the Pioneering Peptide Antibiotics Tyrocidine and Gramicidin S
Cyclic β-sheet decapeptides, such as tyrocidines and gramicidin S, were among the first antibiotics in clinical application. Although they have been used for such a long time, there is virtually no resistance to them, which has led to a renewed interest in this peptide class. Both tyrocidines and gr...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-10-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.00802-18 |