Selection against heteroplasmy explains the evolution of uniparental inheritance of mitochondria.

Why are mitochondria almost always inherited from one parent during sexual reproduction? Current explanations for this evolutionary mystery include conflict avoidance between the nuclear and mitochondrial genomes, clearing of deleterious mutations, and optimization of mitochondrial-nuclear coadaptat...

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Bibliographic Details
Main Authors: Joshua R Christie, Timothy M Schaerf, Madeleine Beekman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4400020?pdf=render