Differential PfEMP1 expression is associated with cerebral malaria pathology.

Plasmodium falciparum is unique among human malarias in its ability to sequester in post-capillary venules of host organs. The main variant antigens implicated are the P. falciparum erythrocyte membrane protein 1 (PfEMP1), which can be divided into three major groups (A-C). Our study was a unique ex...

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Bibliographic Details
Main Authors: Dumizulu L Tembo, Benjamin Nyoni, Rekah V Murikoli, Mavuto Mukaka, Danny A Milner, Matthew Berriman, Stephen J Rogerson, Terrie E Taylor, Malcolm E Molyneux, Wilson L Mandala, Alister G Craig, Jacqui Montgomery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4256257?pdf=render