Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
Bistable switches are a common regulatory motif in cell fate decision-making circuits with two mutually exclusive expression states. Here the authors develop a bistable reporter system and report two additional expression states.
Main Authors: | Xiaona Fang, Qiong Liu, Christopher Bohrer, Zach Hensel, Wei Han, Jin Wang, Jie Xiao |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05071-1 |
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