Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF

Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF

DNA repair is related to many physiological and pathological processes, including pigmentation. Little is known about the role of the transcriptional cofactor Mediator complex in DNA repair and pigmentation. Here, we demonstrate that Mediator MED23 plays an important role in coupling UV-induced DNA...

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Bibliographic Details
Main Authors: Min Xia, Kun Chen, Xiao Yao, Yichi Xu, Jiaying Yao, Jun Yan, Zhen Shao, Gang Wang
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
Mediator complex
MED23
pigmentation
UV
DNA damage and repair
MITF
enhancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717310355

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http://www.sciencedirect.com/science/article/pii/S2211124717310355

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