In Search of Optimal DBS Paradigms to Treat Epilepsy: Bilateral Versus Unilateral Hippocampal Stimulation in a Rat Model for Temporal Lobe Epilepsy

Background: In many temporal lobe epilepsy (TLE) patients both hippocampi are seizure onset zones. These patients are unsuitable candidates for epilepsy surgery but may be amenable to hippocampal deep brain stimulation (DBS). The optimal DBS parameters for these patients are unknown. Recent observat...

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Bibliographic Details
Main Authors: B. Van Nieuwenhuyse, R. Raedt, J. Delbeke, W.J. Wadman, P. Boon, K. Vonck
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Brain Stimulation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X14003957