OptMAVEn-2.0: De novo Design of Variable Antibody Regions Against Targeted Antigen Epitopes
Monoclonal antibodies are becoming increasingly important therapeutic agents for the treatment of cancers, infectious diseases, and autoimmune disorders. However, laboratory-based methods of developing therapeutic monoclonal antibodies (e.g., immunized mice, hybridomas, and phage display) are time-c...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-06-01
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Series: | Antibodies |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4468/7/3/23 |